Having played with iOS 7 for awhile now, I like the overall direction very much, there are just a few small issues that irritate me:
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Home screen backgrounds
This is probably the most annoying part, and a clear sign of Ive not able to imagine bad taste among customers. Because of the very light text you absolute need a background with low contrast to be able to read it easily. Most backgrounds that worked fine in iOS 6 break on iOS 7. Here Apple really should offer a bold text option for the home screen only.
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FaceTime
FaceTime with the dark background looks annoying, it is probably used to differentiate it from the phone app, which actually offers the same functionality, but with a much more friendly face.
Update: FaceTime actually uses your home screen background darkened, it is a bug that causes it to become black.
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Notes
Unlike a lot of other people, I actually liked marker felt as the font. It gave notes that casual feeling, showing us that they are not finished, but mostly just thoughts jotted down to be remembered later. Helvetica Neue Light on the other hand has a very finished, elegant feeling to it, more suitable for beautifully crafted words than incomplete notes.
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Long animation times
The animations to open the home screen could be a bit faster, it makes me feel I am waiting. The app switcher animations on the other work quite well.
In the end these are minor issues once you have changed your home screen background. I am quite positively surprised how fluent the new design language already is.